$ 17.55
Clinical Applications
AdrenalCare pairs glandulars with targeted nutrients to support the body’s response to everyday stressors. Among the comprehensive blend of nutrients are high-potency pantothenic acid and vitamin C, activated B vitamins, and mineral amino acid chelates. Gland and organ tissues are derived from an Argentinian bovine source that ensures safety and purity.*
*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
Wheat, gluten, yeast, soy, dairy products, fish, shellfish, peanuts, tree nuts, egg, ingredients derived from genetically modified organisms (GMOs), artificial colors, artificial sweeteners, or artificial preservatives.
Take two capsules two times daily, or as directed by your healthcare practitioner. Consult your healthcare practitioner prior to use. Individuals taking medication should discuss potential interactions with their healthcare practitioner. Do not use if tamper seal is damaged.
Stress is caused by physiological, psychological, or emotional triggers (stressors) that cause a disturbance in the homeostasis of an organism. How we respond to those stressors (physiologically and psychologically) influences how well we cope with change and with ongoing stress. Structural or physical trauma, distress, poor diet, infection, toxic exposure, leaky gut, births, deaths, lack of sleep, temperature changes, electromagnetic radiation, and allergies or food sensitivities are all potential stressors. Combined, they amount to a total stress level and can ultimately disrupt homeostasis with direct effects on the autonomic nervous system, the hypothalamic-pituitaryadrenal (HPA) axis, and the cardiovascular, metabolic, and immune systems.[1] Specifically, research reveals that prolonged stress has a profound effect on the adrenal glands, lymph nodes, thymus gland, and gastrointestinal system.[2] Endocrinologist Hans Selye identified the various stages of the stress response (alarm, resistance, and exhaustion) and described the entire phenomenon as the general adaptation syndrome (GAS).
Micronutrients, such as vitamins, minerals, and antioxidants, are involved in the majority of metabolic functions in the body. B vitamins are especially important to energy generation within the cellular mitochondria, and a deficiency of any B vitamin can compromise mitochondrial function.[3,4] Riboflavin supports the respiratory chain, niacin supplies protons for oxidative phosphorylation, and pantothenic acid is required for coenzyme A production, metabolic enzyme complex formation, and fatty acid oxidation. increase metabolic demand, energy expenditure, and micronutrient needs.[5] Micronutrient sufficiency and balance have been established as crucial to helping maintain a healthy psychological and physiological response to stress.[6] Unfortunately, experts estimate that a significant proportion of the general population does not consume adequate dietary levels of several micronutrients. Experts suggest that exogenous supplementation can improve micronutrient status and sufficiency and help support a healthy response to stress.*[7]
Clinical research supports the premise that micronutrient supplementation can favorably support the stress response in a variety of circumstances.[7] In a randomized, double-blind, placebo-controlled (RDBPC) trial, high-potency doses of B vitamins and vitamin C along with an array of minerals were studied for their effects on perceived stress scores (measuring one’s self perception of stress) in 215 males aged 30 to 55 years. Results revealed significant improvements on the perceived stress scale (PSS), the profile of mood states (POMS), and the general health questionnaire (GHQ-12) for those taking the multivitamin/mineral supplement.[8] Another RDBPC study of 80 males revealed consistent and statistically significant modulation in anxiety and perceived stress in the men who took a high-potency multivitamin/ mineral supplement compared to those who took the placebo. Participants taking the supplement also reported feeling less tired and better able to concentrate compared to their placebo-taking counterparts.[9] Similar results were achieved in a double-blind, placebo-controlled, double-center study of 300 subjects taking a multivitamin/mineral supplement, with significant improvement in baseline stress scores.[6] The levels of vitamin C, riboflavin, B6, pantothenic acid, and zinc provided in the recommended dose of two AdrenalCare capsules twice daily meets or exceeds the levels used in these clinical studies. The recommended daily dose of four capsules also provides 30 mg of niacin (compared to 50 mg used in studies) and 90 mg of magnesium (compared to 100 mg used in studies).*
AdrenalCare also contains a blend of complementary nutrients and purified glandulars. Rhodiola rosea, chlorella, grape seed extract, magnesium, zinc, chromium, bioflavonoids, and L-tyrosine are present at levels that allow for additional supplementation to round out their profile. Activated B vitamins and Albion® TRAACS® (the real amino acid chelate system) mineral amino acid chelates, along with other chelated minerals, are key features of the formula. Adrenal, parotid, thymus, and spleen glandulars are extracted from an Argentinian bovine source that ensures safety and purity.*
$ 37.80
Clinical Applications
Cortisol Balance helps your body resist and recover from the effects of everyday stress. Components of this multifunctional formula have been shown to support healthy cortisol levels, help alleviate occasional fatigue, promote mental clarity, and support relaxation and restful sleep.*
*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
Does Not Contain
Wheat, gluten, yeast, soy, dairy products, fish, shellfish, peanuts, tree nuts, egg, ingredients derived from genetically modified organisms (GMOs), artificial colors, artificial sweeteners, or artificial preservatives.
Take one capsule twice daily, or as directed by your healthcare practitioner.
Consult your healthcare practitioner prior to use. Individuals taking medication should discuss potential interactions with their healthcare practitioner. Do not use if tamper seal is damaged.
Cortisol Balance is a multifunctional herbal supplement that has far-reaching and complementary benefits for individuals seeking help in dealing with everyday stress. It features a unique combination of clinically tested and patented ingredients, including Relora®, Sensoril®, and Suntheanine®, along with banaba leaf and maral extracts. Together, these herbs help the overstressed body and mind work toward their normal state of balance and resolve many of the biochemical changes that occur as a result of repeated, frequent exposure to stressors and cortisol.*
$ 25.85
Clinical Applications
Hormone Balance delivers a unique, proprietary blend of 8-prenylnaringenin (8-PN) from hops and plantlignan extract at clinically relevant levels. Research suggests lignans and 8-PN can support the body’s natural process of healthy aromatase activity and exert phytoestrogen (e.g., enterolactone) and antioxidant activity. This all-natural formula may support cardiovascular, bone, breast, and prostate health and help relieve normal menopausal discomforts.*
*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
Does Not Contain
Wheat, gluten, corn, soy, animal or dairy products, fish, shellfish, peanuts, tree nuts, egg, ingredients derived from genetically modified organisms (GMOs), artificial colors, artificial sweeteners, or preservatives.
Take one to two capsules daily, or use as directed by your healthcare practitioner. Consult your healthcare practitioner prior to use. Do not use if tamper seal is damaged.
As scientific knowledge advances, it is becoming more evident that a balance of estrogenic and antiestrogenic activities within the body is normal and optimal, has important effects on the health of estrogen-sensitive tissues, and can help relieve normal menopausal symptoms. Reducing abundant estrogenic activity is one way to support balance. Another approach is to offer the body a “weak” estrogen that can support estrogenic activity when it is low or can replace more potent endogenous or exogenous estrogens. Research suggests that the ingredients in Hormone Balance do both.*
8-prenylnaringenin (8-PN)
Hops are the female seed cones of the hop species Humulus lupulus, a medicinal plant that offers a wide range of biologically active components that are used for a variety of purposes. More recently, prenylflavonoids obtained from the lupulin glands of hop cones have become the focus of research. The prenylflavonoid 8-PN has been identified as one of the most potent phytoestrogens because it provides greater activity than other commonly used isoflavone phytoestrogens, such as daidzein and genistein.*
In vitro and in vivo studies conducted in recent years indicate a potential role for 8-PN in relieving common menopausal concerns. In pilot and prospective studies that were randomized and placebo-controlled, postmenopausal women who took 100-250 mcg/day of 8-PN experienced reductions in vasomotor symptoms and other common menopausal discomforts. Furthermore, research in ovariectomized rats indicated that 8-PN produced mild estrogenic effects in vaginal and uterine epithelial tissues. Although further studies are needed, animal and in vitro work show promising effects of 8-PN in cardiovascular, bone, prostate, and breast health. In one study, ovariectomized rats treated with 8-PN or 17 beta-estradiol displayed complete suppression of ovariectomy-induced bone and uterine changes in a qualitatively similar manner.*
Not only does 8-PN offer phytoestrogenic activity, but it has also been observed to affect aromatase—a cytochrome P450 isoenzyme responsible for the conversion of circulating androgens into estrogens. Aromatase is expressed in several tissues, such as breast tissue, where estrogens exert physiological activity. New research suggests that prenylflavonoids interact with aromatase in a manner that positively affects endogenous estradiol biosynthesis and, therefore, the relative balance of other hormones, such as testosterone. Of the flavonoids studied, 8-PN has demonstrated the greatest impact on estrogen biosynthesis during in vitro experimentation. It has been postulated that providing phytoestrogens while modulating the production of potent endogenous estrogens may result in safer, more balanced estrogenic activity. Brunelli et al. investigated the influences of 8-PN on epidermal growth factor (EGF)-elicited pathways in certain breast cells and demonstrated that 8-PN interferes with EGF-induced cell proliferation in estrogen-receptor positive cells.*
HMRlignan™
Plant lignans are phytonutrients commonly found in small amounts in unrefined whole grains, seeds, nuts, vegetables, berries, and beverages, such as tea and coffee. The friendly bacteria in our intestines convert plant lignans into the “human” lignans called enterodiol and enterolactone. HMRlignan is a concentrated, naturally occurring plant lignan called 7-hydroxymatairesinol, which is derived from the Norway spruce (Picea abies). In humans, 7-hydroxymatairesinol is a direct metabolic precursor of enterolactone.*
Enterolactone is a phytoestrogen that binds to estrogen receptors and has both weak estrogenic and weak antiestrogenic effects. The latter accounts for much of its cell-protective capacity. Additionally, in vitro work has demonstrated that enterolactone affects aromatase and the biosynthesis of estrogen and has strong free radical scavenging and antioxidant properties. The protective effect of lignans and enterolactone on tissues, including those of the prostate and breast, is encouraging. At the same time, the estrogenicity of HMR and enterolactone, although milder than estradiol, offers promising applications for women with menopausal concerns. For instance, in a randomized, single-blind, parallel group pilot study, 20 menopausal women taking 50 mg/d of hydroxymatairesinol for eight weeks experienced half as many hot flushes as compared to pretreatment. Furthermore, high serum enterolactone has repeatedly been associated with cardiovascular health.*